Profhilo vs Botox:
Which Treatment is Right for You?

Two of the most popular non-surgical aesthetic treatments available today are Profhilo and Botox (anti-wrinkle injections). Both are injectable treatments, both deliver impressive results, and both are offered at The London Aesthetic Clinic — but they work in very different ways and target different concerns. Understanding the distinction is key to choosing the right treatment for you.

In this guide, our expert practitioners break down the key differences between Profhilo and Botox, explain what each treatment is best suited for, and help you decide which option — or combination — is right for your aesthetic goals.

What is Profhilo?

Profhilo is a revolutionary injectable bio-remodelling treatment made from a highly concentrated form of hyaluronic acid. Unlike traditional dermal fillers, Profhilo doesn't add volume or fill lines — instead, it spreads beneath the skin to deeply hydrate the tissue and stimulate the production of collagen and elastin.

The result is a significant improvement in skin quality, texture, and radiance. Skin appears plumper, more hydrated, and more youthful — with a natural glow that comes from within. Profhilo is particularly effective for treating skin laxity (sagging or crepey skin) on the face, neck, and décolletage.

A standard Profhilo course consists of two treatment sessions, spaced four weeks apart. Results typically last up to six months, after which a maintenance session is recommended.

What is Botox (Anti-Wrinkle Injections)?

Botox — more accurately referred to as anti-wrinkle injections — uses a purified form of botulinum toxin to temporarily relax specific facial muscles. When these muscles are relaxed, the overlying skin smooths out, reducing the appearance of dynamic wrinkles — the lines that form when you make facial expressions.

The most common treatment areas are the forehead, frown lines (the "11s" between the brows), and crow's feet around the eyes. Anti-wrinkle injections can also be used for a brow lift, to reduce a gummy smile, to slim the jawline (masseter reduction), and to treat excessive sweating (hyperhidrosis).

Results from anti-wrinkle injections typically last 3–6 months. Regular treatments can help to train the muscles over time, meaning results may last longer with repeated sessions.

Profhilo vs Botox: Which Should You Choose?

The right treatment for you depends entirely on your primary concern:

• Choose Profhilo if:

  • Your skin feels dehydrated, dull, or lacklustre

  • You have skin laxity or crepey skin texture

  • You want to improve overall skin quality and radiance

  • You're looking for a natural, glowing result without changing your features

• Choose Botox if:

  • You have visible dynamic wrinkles (forehead lines, frown lines, crow's feet)

  • You want to prevent new lines from forming

  • You're looking for a quick, effective treatment with no downtime

  • You want to address specific areas of facial movement

Can You Have Profhilo and Botox Together?

Absolutely — and in fact, combining Profhilo and anti-wrinkle injections is one of the most popular treatment combinations at The London Aesthetic Clinic. The two treatments complement each other beautifully: Botox addresses dynamic wrinkles and prevents new ones from forming, while Profhilo improves the overall quality, hydration, and radiance of the skin.

Together, they deliver a comprehensive facial rejuvenation that looks completely natural — addressing both the movement-related concerns and the underlying skin quality simultaneously. Many of our clients describe this combination as their "secret weapon" for maintaining a youthful, refreshed appearance.